Thursday, December 20, 2007

Dexedrine/Food Interactions

From Food Medication Interactions 14th Edition:

pg119
Dexedrine ANTI-ADHD, ANTINARCOLEPSY See lising for Amphetamines p 37

Amphetamines
Adderall/Adderall XR (dextroamphetamine & amphetamine)
Adderall (Tab- sucrose, lactose, cornstarch)
Adderall XR (Cap- sugar spheres [sucrose & starch], Kosher gelatin)
Dexedrine (dextroamphetamine Spansule (SR)-cetyal alcohol, sugar spheres [sucrose & starch] Tab- lactose, starch, sucrose, mineral oil, tartrazine

ANTI-ADHD, ANTINARCOLEPSY, Appetite Depressant, CNS Stimulant
Drug: Swallow SR form whole early in the day. As anorectic, take 1/2-1 hr before meals. For other uses (eg ADHD) take with or after meal.
Diet: Limit caffeine, see p 442. (pg 442 is a listing of caffeine amounts in common caffeinated drinks) Avoid high dose Vitamin C. Acidifying agents decrease absorption, increase excretion, & decrease half life of the drug. Alkalinizing agents (eg Na Bicarbonate, CaCO3, antacids) increase absorption, decrease excretion, & increase half life. As an anorectic, low calorie diet is essential.
Nutr: (This section is hard to explain without having the actual book in hand, and it doesn't mention anything pertinent to this post, so I'm leaving it out)
Oral/GI: Dry Mouth, metallic taste, stomach pain/cramps, nausea, diarrhea, constipation.
Special Conditions: Avoid alcohol. Not with lactation. Caution with hypertension. May be habit forming. Caution with seizures. Caution with geriatric.
Pregnancy: Category C (Category C is the FDA pregnancy category relating to this drug. Cat C specifically means that animal studies have shown adverse effects on fetus, but there are no controlled studies in women. Drugs in this category are given only if potential justifies risk to fetus)
Other: Palpitations, restlessness, tremor, increased blood pressure, nervousness, chills, dizziness, insomnia, blurred vision, tachycardia, headache, increased sweating, motor or verbal tics, euphoria, diskinesia, over stimulation.
Blood/Serum: Increased corticosteroids, Increased T4 with heavy use.
Urinary: False steroid results.
Monitor: Blood pressure. Children's growth.



Okay, so as you can see, it doesn't say anywhere "No Fruit Juice." It DOES say to avoid things with high vitamin C, and implies that you should avoid acidifying agents. This means that there are certain juices you should avoid completely (probably like Orange Juice, and most citrus juices), but there ARE others that are conceivable choices. Most fruit does have high vitamin C content, but some are not super crazy. Don't just go out and buy these, but look into blueberry juice, pomegranate juice, and cranberry juice as possible safe alternatives. I am going to have to find a different text before I can say for certain what would be safe for use, but feel free to do your own research on those three as well as any others that you think may be possible choices.

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